Cultured Red Blood Cells
The advantages of cRBCs
Thanks to the conditions of their ex vivo generation, cultured Red Blood Cells (cRBCs) exhibit numerous advantages over red blood cells obtained from donated blood.
Better transfusion efficiency
The lifespan of a population of cultured red blood cells (RBCs) is greater than that of a population of native red blood cells: the RBCs are all young, while the native RBCs are very heterogeneous in age. This characteristic is major because it results in higher transfusion efficiency.
This will reduce the number of transfusions and therefore:
- improve the quality of life of multi transfused patients.
- reduce support costs.
Reduced risk of immunization
Currently, perfectly compatible red blood cells needs are not always met.
Selection of donors on the main blood group systems will make it possible to respond to transfusion deadlock situations by reducing the risks of alloimmunization in concerned populations.
A reduction in infectious risks
By reducing the number of different donors, the risk of transmitting infectious agents will be reduced.
For example: during the Covid-19 pandemic, blood collections decreased by 30 to 60%.
Hematopoietic stem cells are frozen and stored for years, allowing production to be adjusted as needed.